Welcome Comparative Effectiveness Research on Cancer in Texas (CERCIT)
The goal of CERCIT is to find evidence that will help patients and their physicians make individualized decisions about the best cancer care options, including screening, treatment and end of life care in cancer.
CERCIT is a multidisciplinary consortium of investigators at the University of Texas Medical Branch (UTMB), MD Anderson Cancer Center (MDACC), UT Health Science Center at Houston (UTHealth), UT Southwestern Medical Center in Dallas (UTSW), and the Texas Department of State Health Services Texas Cancer Registry. CERCIT is funded by the Cancer Prevention Research Institute of Texas (CPRIT).
by UTMB CERCIT, November 2016
The size and diversity of Texas present substantial challenges to the delivery of cancer care throughout the state. The CERCIT Knowledge Translation Core produced the following report and online resources that map population, economic and health care characteristics of diverse geographic areas in Texas that are relevant to the delivery of cancer care.
Read More: Demographic Variations in Texas
by UTMB CERCIT, September 2016
A multi-institutional group, led by James S. Goodwin, MD, has been awarded a second five years of funding for "Comparative Effectiveness Research on Cancer in Texas" (CERCIT). The $6 million grant is from the Cancer Prevention Research Institute of Texas. The CERCIT renewal will build on our analyses of administrative data but expand our methods to better measure individual patient characteristics and include information on patient preferences and patient reported outcomes. Our goal is to generate evidence that will help patients and their physicians make individualized decisions about the best cancer care options for each patient. These choices include screening, treatment and end of life care in cancer.
Read More: CERCIT Renewal
by Rice University Press Release
HOUSTON – (July 25, 2016) – Regions in Texas differ widely in adherence to recommended cancer treatment for elderly patients, according to a study by researchers at Rice University and the University of Texas MD Anderson Cancer Center.
These differences are not due to the availability of treatment specialists or the presence of teaching hospitals, the study found. The absence of consistent explanations for these treatment differences suggests that variations like these are likely to occur elsewhere nationwide.
"Texans are no better off in one city versus another in terms of treatment across a broad range of cancers," said Vivian Ho, the chair in health economics at Rice's Baker Institute for Public Policy and director of the institute's Center for Health and Biosciences, who co-authored the study. "One might have expected Houston residents to receive better treatment because of MD Anderson's presence, but any beneficial effects could be offset by a large number of elderly in Houston not being treated there." The research findings were published in the journal BMC Health Services Research.
2016 CERCIT Publications
|Chavez-MacGregor, M., Clarke, C. A., Lichtensztajn, D. Y., & Giordano, S. H. (2016). Delayed Initiation of Adjuvant Chemotherapy Among Patients With Breast Cancer. JAMA Oncol, 2(3), 322-329. doi:10.1001/jamaoncol.2015.3856||PMID26659132|
|Dimou, F., Sineshaw, H., Parmar, A. D., Tamirisa, N. P., Jemal, A., & Riall, T. S. (2016). Trends in Receipt and Timing of Multimodality Therapy in Early-Stage Pancreatic Cancer. J Gastrointest Surg, 20(1), 93-103; discussion 103. doi:10.1007/s11605-015-2952-7||PMID26503262|
|Elting LS, Xu Y, Chavez-MacGregor M, Giordano SH. Granulocyte growth factor use in elderly patients with non-Hodgkin's lymphoma in the United States: adherence to guidelines and comparative effectiveness. J Supp. Care Cancer, 2016 Jan 3 24(6), 2695-2706.||PMID26797253|
|Esselen, K. M., Cronin, A. M., Bixel, K., Bookman, M. A., Burger, R. A., Cohn, D. E., . . . Wright, A. A. (2016). Use of CA-125 Tests and Computed Tomographic Scans for Surveillance in Ovarian Cancer. JAMA Oncol, 2(11), 1427-1433. doi:10.1001/jamaoncol.2016.1842||PMID27442965|
|Goodwin, J. S., Sheffield, K., Li, S., & Tan, A. (2016). Receipt of Cancer Screening Is a Predictor of Life Expectancy. J Gen Intern Med, 31(11), 1308-1314. doi:10.1007/s11606-016-3787-y||PMID27364834|
|Ho V, Ku-Goto MH, Zhao H, Hoffman E, Smith B, Giordano S. Regional differences in recommended cancer treatment for the elderly. BMC Health Services Research, 2016 16:262 DOI 10.1186/s12913-016-1534-z||Download PDF|
|Huo, J., Giordano, S. H., Smith, B. D., Shaitelman, S. F., & Smith, G. L. (2016). Contemporary Toxicity Profile of Breast Brachytherapy Versus External Beam Radiation After Lumpectomy for Breast Cancer. Int J Radiat Oncol Biol Phys, 94(4), 709-718. doi:10.1016/j.ijrobp.2015.12.013||PMID26972643|
|Huo, J., Smith, B. D., Giordano, S. H., Reece, G. P., & Tina Shih, Y. C. (2016). A comparison of patient-centered economic and clinical outcomes of post-mastectomy breast reconstruction between obese and non-obese patients. Breast, 30, 118-124. doi:10.1016/j.breast.2016.09.004||PMID27697676|
|Kehl, K. L., Shen, C., Litton, J. K., Arun, B., & Giordano, S. H. (2016). Rates of BRCA1/2 mutation testing among young survivors of breast cancer. Breast Cancer Res Treat, 155(1), 165-173. doi:10.1007/s10549-015-3658-y||PMID26706041|
|Lewis, Z. H., Ottenbacher, K. J., Fisher, S. R., Jennings, K., Brown, A. F., Swartz, M. C., & Lyons, E. J. (2016). Testing Activity Monitors' Effect on Health: Study Protocol for a Randomized Controlled Trial Among Older Primary Care Patients. JMIR Res Protoc, 5(2), e59. doi:10.2196/resprot.5454||PMID27129602|
|Lewis, Z. H., Swartz, M. C., & Lyons, E. J. (2016). What's the Point?: A Review of Reward Systems Implemented in Gamification Interventions. Games Health J, 5(2), 93-99. doi:10.1089/g4h.2015.0078||PMID26812253|
|Lin, S. H., Zhang, N., Godby, J., Wang, J., Marsh, G. D., Liao, Z., . . . Giordano, S. H. (2016). Radiation modality use and cardiopulmonary mortality risk in elderly patients with esophageal cancer. Cancer, 122(6), 917-928. doi:10.1002/cncr.29857||PMID26716915|
|Lowenstein, L. M., Richards, V. F., Leal, V. B., Housten, A. J., Bevers, T. B., Cantor, S. B., . . . Volk, R. J. (2016). A brief measure of Smokers' knowledge of lung cancer screening with low-dose computed tomography. Prev Med Rep, 4, 351-356. doi:10.1016/j.pmedr.2016.07.008||PMID27512650|
|Lyons, E. J., Baranowski, T., Basen-Engquist, K. M., Lewis, Z. H., Swartz, M. C., Jennings, K., & Volpi, E. (2016). Testing the effects of narrative and play on physical activity among breast cancer survivors using mobile apps: study protocol for a randomized controlled trial. BMC Cancer, 16, 202. doi:10.1186/s12885-016-2244-y||PMID26960972|
|Mehta, H. B., Parmar, A. D., Adhikari, D., Tamirisa, N. P., Dimou, F., Jupiter, D., & Riall, T. S. (2016). Relative impact of surgeon and hospital volume on operative mortality and complications following pancreatic resection in Medicare patients. J Surg Res, 204(2), 326-334. doi:10.1016/j.jss.2016.05.008||PMID27565068|
|Meyer, L. A., Cronin, A. M., Sun, C. C., Bixel, K., Bookman, M. A., Cristea, M. C., . . . Wright, A. A. (2016). Use and Effectiveness of Neoadjuvant Chemotherapy for Treatment of Ovarian Cancer. J Clin Oncol. doi:10.1200/JCO.2016.68.1239||PMID27601552|
|Nayak, P., Luo, R., Elting, L., Zhao, H., & Suarez-Almazor, M. E. (2016). Impact of Rheumatoid Arthritis on the Mortality of Elderly Patients who Develop Cancer: A Population-Based Study. Arthritis Care Res (Hoboken). doi:10.1002/acr.22997||PMID27483088|
|Nayak, P., Vernon, S. W., Savas, L. S., Basen-Engquist, K., Morgan, R. O., & Elting, L. S. (2016). Functional Impairment and Physical Activity Adherence Among Gynecologic Cancer Survivors: A Population-Based Study. Int J Gynecol Cancer, 26(2), 381-388. doi:10.1097/IGC.0000000000000620||PMID26807568|
|Raber, M., Swartz, M. C., Santa Maria, D., O'Connor, T., Baranowski, T., Li, R., & Chandra, J. (2016). Parental involvement in exercise and diet interventions for childhood cancer survivors: a systematic review. Pediatr Res, 80(3), 338-346. doi:10.1038/pr.2016.84||PMID27064243|
|Sharma, G., Nishi, S. P., Lin, Y. L., Kuo, Y. F., Goodwin, J. S., & Riall, T. S. (2016). Pattern of Imaging after Lung Cancer Resection. 1992-2005. Ann Am Thorac Soc, 13(9), 1559-1567. doi:10.1513/AnnalsATS.201511-768OC||PMID27243464|
|Shirvani, S. M., Jiang, J., Likhacheva, A., Hoffman, K. E., Shaitelman, S. F., Caudle, A., . . . Smith, B. D. (2016). Trends in Local Therapy Utilization and Cost for Early-Stage Breast Cancer in Older Women: Implications for Payment and Policy Reform. Int J Radiat Oncol Biol Phys, 95(2), 605-616. doi:10.1016/j.ijrobp.2016.01.059||PMID27034179|
|Smith, B. D., Jiang, J., Shih, Y. C., Giordano, S. H., Huo, J., Jagsi, R., . . . Shirvani, S. M. (2017). Cost and Complications of Local Therapies for Early-Stage Breast Cancer. J Natl Cancer Inst, 109(1). doi:10.1093/jnci/djw178||PMID27678203|
|Smith, G. L. (2016). Toward Minimizing Overtreatment and Undertreatment of Ductal Carcinoma In Situ in the United States. J Clin Oncol, 34(11), 1172-1174. doi:10.1200/JCO.2015.66.2064||PMID26884563|
|Swartz, M. C., Basen-Engquist, K. M., Markham, C., Lyons, E. J., Cox, M., Chandra, J., . . . Swank, P. R. (2016). Psychometric Analysis of the Three-Factor Eating Questionnaire-R18V2 in Adolescent and Young Adult-Aged Central Nervous System Tumor Survivors. J Adolesc Young Adult Oncol, 5(3), 278-285. doi:10.1089/jayao.2015.0058||PMID27042872|
|Volk, R. J., Linder, S. K., Lopez-Olivo, M. A., Kamath, G. R., Reuland, D. S., Saraykar, S. S., . . . Pignone, M. P. (2016). Patient Decision Aids for Colorectal Cancer Screening: A Systematic Review and Meta-analysis. Am J Prev Med. doi:10.1016/j.amepre.2016.06.022||PMID27593418|
|Williams, S. B., Duan, Z., Chamie, K., Hoffman, K. E., Smith, B. D., Hu, J. C., . . . Giordano, S. H. (2016). Risk of hospitalisation after primary treatment for prostate cancer. BJU Int. doi:10.1111/bju.13647||PMID27561186|
|Zanwar, P., Lin, Y. L., Kuo, Y. F., & Goodwin, J. S. (2016). Downstream tests, treatments, and annual direct payments in older men cared for by primary care providers with high or low prostate-specific antigen screening rates using 100 percent Texas U.S. Medicare public insurance claims data: a retrospective cohort study. BMC Health Serv Res, 16, 17. doi:10.1186/s12913-016-1265-1||PMID26772175|
A Workshop Presented by James S. Goodwin, MD and others at UTMB
Fun with Medicare Part D Data
A CERCIT Workshop presented by James S. Goodwin, MD, August 2014
Shared Decision Making in Cancer Care
A CERCIT Workshop presented by Nina Tamirisa, MD, August 2014
The Use of Surgery in the Elderly for Management of Metastatic Epidural Spinal Cord Compression
A CERCIT Workshop presented by Justin E. Bird, MD, June 2014
Population-Based Assessment of Breast Reconstruction
A CERCIT Workshop presented by Ben Smith, MD, June 2014
Reports and Special Publications
Surveillance Patterns Following Lung Cancer Resection [PDF]: This report describes the current population-based trends in surveillance practices and the use of these modalities in patients with non-small cell lung cancer (NSCLC) following curative resection.
Comparative Effectiveness of MRI vs. Mammography Alone in Patients Undergoing Breast-Conserving Therapy for Breast Cancer [PDF]: This report compares the effectiveness of MRI vs. mammography alone in patients undergoing breast-conserving therapy for breast cancer
Hispanic Cancer Report [PDF]: From A quarterly publication of the Texas Public Health Association (TPHA) Supplement, Fall 2013, A Comprehensive Report on Cancer among Hispanics in Texas.
CERCIT Featured in the Texas Public Health Journal Summer 2013
Using research to keep Texans informed about cancer care – that is at the heart of CERCIT (Comparative Effectiveness Research on Cancer in Texas). A description of this project and selected articles from its four research areas are featured in the Spring 2013 issue of the Texas Public Health Journal, a quarterly publication of the Texas Public Health Association (pages 22-55):
Just how much does cancer cost in Texas? [PDF] Texas Public Health Journal, Vol 63, Issue 4, Fall 2011. Findings are reported in the Cost of Cancer in Texas, 2005 [PDF] published by the Texas Cancer Council.
CERCIT Workshop Presentations
In the first five years of CERCIT, we offered clinician-scientist training in Comparative Effectiveness Research on Cancer in Texas.
Trainees attended monthly workshops. A selection of those workshop presentations are now available as resources linked below: