Welcome Comparative Effectiveness Research on Cancer in Texas (CERCIT)
The goal of CERCIT is to find evidence that will help patients and their physicians make individualized decisions about the best cancer care options, including screening, treatment and end of life care in cancer.
CERCIT is a multidisciplinary consortium of investigators at the University of Texas Medical Branch (UTMB), MD Anderson Cancer Center (MDACC), UT Health Science Center at Houston (UTHealth), UT Southwestern Medical Center in Dallas (UTSW), and the Texas Department of State Health Services Texas Cancer Registry. CERCIT is funded by the Cancer Prevention Research Institute of Texas (CPRIT).
by UTMB CERCIT, November 2016
The size and diversity of Texas present substantial challenges to the delivery of cancer care throughout the state. The CERCIT Knowledge Translation Core produced the following report and online resources that map population, economic and health care characteristics of diverse geographic areas in Texas that are relevant to the delivery of cancer care.
Read More: Demographic Variations in Texas
by UTMB CERCIT, September 2016
A multi-institutional group, led by James S. Goodwin, MD, has been awarded a second five years of funding for "Comparative Effectiveness Research on Cancer in Texas" (CERCIT). The $6 million grant is from the Cancer Prevention Research Institute of Texas. The CERCIT renewal will build on our analyses of administrative data but expand our methods to better measure individual patient characteristics and include information on patient preferences and patient reported outcomes. Our goal is to generate evidence that will help patients and their physicians make individualized decisions about the best cancer care options for each patient. These choices include screening, treatment and end of life care in cancer.
Read More: CERCIT Renewal
by Rice University Press Release
HOUSTON – (July 25, 2016) – Regions in Texas differ widely in adherence to recommended cancer treatment for elderly patients, according to a study by researchers at Rice University and the University of Texas MD Anderson Cancer Center.
These differences are not due to the availability of treatment specialists or the presence of teaching hospitals, the study found. The absence of consistent explanations for these treatment differences suggests that variations like these are likely to occur elsewhere nationwide.
"Texans are no better off in one city versus another in terms of treatment across a broad range of cancers," said Vivian Ho, the chair in health economics at Rice's Baker Institute for Public Policy and director of the institute's Center for Health and Biosciences, who co-authored the study. "One might have expected Houston residents to receive better treatment because of MD Anderson's presence, but any beneficial effects could be offset by a large number of elderly in Houston not being treated there." The research findings were published in the journal BMC Health Services Research.
2017 CERCIT Publications
|Chavez-MacGregor, M., Mittendorf, E. A., Clarke, C. A., Lichtensztajn, D. Y., Hunt, K. K., & Giordano, S. H. (2017). Incorporating Tumor Characteristics to the American Joint Committee on Cancer Breast Cancer Staging System. Oncologist. doi:10.1634/theoncologist.2017-0116||PMID28592619|
|Fang, P., He, W., Gomez, D. R., Hoffman, K. E., Smith, B. D., Giordano, S. H., . . . Smith, G. L. (2017). Influence of Age on Guideline-Concordant Cancer Care for Elderly Patients in the United States. Int J Radiat Oncol Biol Phys, 98(4), 748-757. doi:10.1016/j.ijrobp.2017.01.228||PMID28366580|
|Goodwin, J. S., Zhou, J., Kuo, Y. F., & Baillargeon, J. (2017). Risk of Jaw Osteonecrosis After Intravenous Bisphosphonates in Cancer Patients and Patients Without Cancer. Mayo Clin Proc, 92(1), 106-113. doi:10.1016/j.mayocp.2016.09.015||PMID27876314|
|Hoffman, A. S., Lowenstein, L. M., Kamath, G. R., Housten, A. J., Leal, V. B., Linder, S. K., . . . Volk, R. J. (2017). An entertainment-education colorectal cancer screening decision aid for African American patients: A randomized controlled trial. Cancer, 123(8), 1401-1408. doi:10.1002/cncr.30489||PMID28001305|
|Huo J, Chu Y, Chamie K, Smaldone MC, Boorjian SA, Baillargeon JG, Kuo YF, Kerr P, O'Malley P, Orihuela E, Tyler DS, Freedland SJ, Giordano SH, Vikram R, Kamat AM, Williams SB. Increased Utilization of Positron Emission Tomography/Computed Tomography (PET/CT) Imaging and Its Economic Impact for Patients Diagnosed With Bladder Cancer. Clin Genitourin Cancer. 2017 Jul 26. pii: S1558-7673(17)30215-X. doi: 10.1016/j.clgc.2017.07.018. [Epub ahead of print] PubMed||PMID28826932|
|Lyons, E. J., Swartz, M. C., Lewis, Z. H., Martinez, E., & Jennings, K. (2017). Feasibility and Acceptability of a Wearable Technology Physical Activity Intervention With Telephone Counseling for Mid-Aged and Older Adults: A Randomized Controlled Pilot Trial. JMIR Mhealth Uhealth, 5(3), e28. doi:10.2196/mhealth.6967||PMID28264796|
|Mehta, H. B., Vargas, G. M., Adhikari, D., Dimou, F., & Riall, T. S. (2017). Comparative effectiveness of chemotherapy vs resection of the primary tumour as the initial treatment in older patients with Stage IV colorectal cancer. Colorectal Dis, 19(6), O210-O218. doi:10.1111/codi.13659||PMID28304120|
|Mittendorf, E. A., Chavez-MacGregor, M., Vila, J., Yi, M., Lichtensztajn, D. Y., Clarke, C. A., . . . Hunt, K. K. (2017). Bioscore: A Staging System for Breast Cancer Patients that Reflects the Prognostic Significance of Underlying Tumor Biology. Ann Surg Oncol. doi:10.1245/s10434-017-6009-x||PMID28726077|
|Nayak, P., Luo, R., Elting, L., Zhao, H., & Suarez-Almazor, M. E. (2017). Impact of Rheumatoid Arthritis on the Mortality of Elderly Patients Who Develop Cancer: A Population-Based Study. Arthritis Care Res (Hoboken), 69(1), 75-83. doi:10.1002/acr.22997||PMID27483088|
|Ninan, M. J., Liu, Y., Kuo, Y. F., & Goodwin, J. S. (2017). Hospitalization for Toxicity in Patients Treated With Rituximab. Am J Clin Oncol, 40(2), 125-132. doi:10.1097/COC.0000000000000127||PMID25238286|
|Pasalic, D., Jiang, J., Jagsi, R., Giordano, S. H., & Smith, B. D. (2017). Association of Insurance Status with the Use of Immediate Breast Reconstruction in Women with Breast Cancer. Plast Reconstr Surg Glob Open, 5(7), e1360. doi:10.1097/GOX.0000000000001360||PMID28831333|
|Shaitelman, S. F., Howell, R. M., & Smith, B. D. (2017). Effects of Smoking on Late Toxicity From Breast Radiation. J Clin Oncol, 35(15), 1633-1635. doi:10.1200/JCO.2017.72.2660||PMID28319432|
|Shen, C., Kehl, K. L., Zhao, B., Simon, G. R., Zhou, S., & Giordano, S. H. (2017). Utilization Patterns and Trends in Epidermal Growth Factor Receptor (EGFR) Mutation Testing Among Patients With Newly Diagnosed Metastatic Lung Cancer. Clin Lung Cancer, 18(4), e233-e241. doi:10.1016/j.cllc.2016.11.002||PMID28024927|
|Suidan, R. S., He, W., Sun, C. C., Zhao, H., Ramondetta, L. M., Badgwell, B. D., . . . Meyer, L. A. (2017). Treatment Patterns, Outcomes, and Costs for Bowel Obstruction in Ovarian Cancer. Int J Gynecol Cancer. doi:10.1097/IGC.0000000000000998||PMID28574929|
|Swartz, M. C., Lewis, Z. H., Lyons, E. J., Jennings, K., Middleton, A., Deer, R. R., . . . Goodwin, J. S. (2017). Effect of Home- and Community-Based Physical Activity Interventions on Physical Function Among Cancer Survivors: A Systematic Review and Meta-Analysis. Arch Phys Med Rehabil. doi:10.1016/j.apmr.2017.03.017||PMID28427925|
|Taylor, J. S., Rajan, S. S., Zhang, N., Meyer, L. A., Ramondetta, L. M., Bodurka, D. C., . . . Giordano, S. H. (2017). End-of-Life Racial and Ethnic Disparities Among Patients With Ovarian Cancer. J Clin Oncol, 35(16), 1829-1835. doi:10.1200/JCO.2016.70.2894||PMID28388292|
|Williams, S. B., Huo, J., Chamie, K., Smaldone, M. C., Kosarek, C. D., Fang, J. E., . . . Chapin, B. F. (2017). Discerning the survival advantage among patients with prostate cancer who undergo radical prostatectomy or radiotherapy: The limitations of cancer registry data. Cancer, 123(9), 1617-1624. doi:10.1002/cncr.30506||PMID28099688|
|Williams, S. B., Huo, J., Chapin, B. F., Smith, B. D., & Hoffman, K. E. (2017). Impact of urologists' ownership of radiation equipment in the treatment of prostate cancer. Prostate Cancer Prostatic Dis. doi:10.1038/pcan.2017.9||PMID28349981|
|Williams, S. B., Huo, J., Dafashy, T. J., Ghaffary, C. K., Baillargeon, J. G., Morales, E. E., . . . Kamat, A. M. (2017). Survival differences among patients with bladder cancer according to sex: Critical evaluation of radical cystectomy use and delay to treatment. Urol Oncol, 35(10), 602 e601-602 e609. doi:10.1016/j.urolonc.2017.05.022||PMID28647395|
A Workshop Presented by James S. Goodwin, MD and others at UTMB
Fun with Medicare Part D Data
A CERCIT Workshop presented by James S. Goodwin, MD, August 2014
Shared Decision Making in Cancer Care
A CERCIT Workshop presented by Nina Tamirisa, MD, August 2014
The Use of Surgery in the Elderly for Management of Metastatic Epidural Spinal Cord Compression
A CERCIT Workshop presented by Justin E. Bird, MD, June 2014
Population-Based Assessment of Breast Reconstruction
A CERCIT Workshop presented by Ben Smith, MD, June 2014
Reports and Special Publications
Surveillance Patterns Following Lung Cancer Resection [PDF]: This report describes the current population-based trends in surveillance practices and the use of these modalities in patients with non-small cell lung cancer (NSCLC) following curative resection.
Comparative Effectiveness of MRI vs. Mammography Alone in Patients Undergoing Breast-Conserving Therapy for Breast Cancer [PDF]: This report compares the effectiveness of MRI vs. mammography alone in patients undergoing breast-conserving therapy for breast cancer
Hispanic Cancer Report [PDF]: From A quarterly publication of the Texas Public Health Association (TPHA) Supplement, Fall 2013, A Comprehensive Report on Cancer among Hispanics in Texas.
CERCIT Featured in the Texas Public Health Journal Summer 2013
Using research to keep Texans informed about cancer care – that is at the heart of CERCIT (Comparative Effectiveness Research on Cancer in Texas). A description of this project and selected articles from its four research areas are featured in the Spring 2013 issue of the Texas Public Health Journal, a quarterly publication of the Texas Public Health Association (pages 22-55):
Just how much does cancer cost in Texas? [PDF] Texas Public Health Journal, Vol 63, Issue 4, Fall 2011. Findings are reported in the Cost of Cancer in Texas, 2005 [PDF] published by the Texas Cancer Council.
CERCIT Workshop Presentations
In the first five years of CERCIT, we offered clinician-scientist training in Comparative Effectiveness Research on Cancer in Texas.
Trainees attended monthly workshops. A selection of those workshop presentations are now available as resources linked below: